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Substance P (7-11)

CAS No. 51165-05-0

Substance P (7-11) ( —— )

产品货号. M30419 CAS No. 51165-05-0

Substance P (7-11) is a C-terminal fragment of Substance P, which can cause an increase in the intracellular calcium concentration as measured by the fluorescent dye Fura-2. In addition, the C-terminal fragment of SP, SP-(7-11), increased PGE2 and collagenase production at concentrations greater than 1 mM.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥281 有现货
5MG ¥461 有现货
10MG ¥814 有现货
25MG ¥1354 有现货
50MG ¥2038 有现货
100MG ¥2808 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
2MG ¥281 有现货
5MG ¥461 有现货
10MG ¥814 有现货
25MG ¥1354 有现货
50MG ¥2038 有现货
100MG ¥2808 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货

生物学信息

  • 产品名称
    Substance P (7-11)
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Substance P (7-11) is a C-terminal fragment of Substance P, which can cause an increase in the intracellular calcium concentration as measured by the fluorescent dye Fura-2. In addition, the C-terminal fragment of SP, SP-(7-11), increased PGE2 and collagenase production at concentrations greater than 1 mM.
  • 产品描述
    Substance P (7-11) is a C-terminal fragment of Substance P, which can cause an increase in the intracellular calcium concentration as measured by the fluorescent dye Fura-2. In addition, the C-terminal fragment of SP, SP-(7-11), increased PGE2 and collagenase production at concentrations greater than 1 mM.(In Vitro):Substance P (7-11) increases PGE2 and collagenase production at concentrations greater than 1 μM. Substance P (7-11), but not intact SP, SP-(1-4), SP-(1-6), SP- (8-11) or SP-(9-1 1), nor the tachykinins NKA and NKB, causes an increase in the intracellular calcium concentration as measured by the fluorescent dye Fura-2. The maximal change in intracellular calcium induced by 10 μM Substance P (7-11) was 140±30 nM.
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    ——
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    51165-05-0
  • 分子量
    612.8
  • 分子式
    C31H44N6O5S
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    ——
  • 化学全称
    Sequence:Phe-Phe-Gly-Leu-Met-NH2

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

Halliday DA, et al. The substance P fragment SP-(7-11) increases prostaglandin E2, intracellular Ca2+ and collagenase production in bovine articular chondrocytes. Biochem J. 1993 May 15;292 ( Pt 1):57-62.
产品手册
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