Substance P (7-11)
CAS No. 51165-05-0
Substance P (7-11) ( —— )
产品货号. M30419 CAS No. 51165-05-0
Substance P (7-11) is a C-terminal fragment of Substance P, which can cause an increase in the intracellular calcium concentration as measured by the fluorescent dye Fura-2. In addition, the C-terminal fragment of SP, SP-(7-11), increased PGE2 and collagenase production at concentrations greater than 1 mM.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
2MG | ¥281 | 有现货 |
|
5MG | ¥461 | 有现货 |
|
10MG | ¥814 | 有现货 |
|
25MG | ¥1354 | 有现货 |
|
50MG | ¥2038 | 有现货 |
|
100MG | ¥2808 | 有现货 |
|
200MG | 获取报价 | 有现货 |
|
500MG | 获取报价 | 有现货 |
|
2MG | ¥281 | 有现货 |
|
5MG | ¥461 | 有现货 |
|
10MG | ¥814 | 有现货 |
|
25MG | ¥1354 | 有现货 |
|
50MG | ¥2038 | 有现货 |
|
100MG | ¥2808 | 有现货 |
|
200MG | 获取报价 | 有现货 |
|
500MG | 获取报价 | 有现货 |
|
生物学信息
-
产品名称Substance P (7-11)
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述Substance P (7-11) is a C-terminal fragment of Substance P, which can cause an increase in the intracellular calcium concentration as measured by the fluorescent dye Fura-2. In addition, the C-terminal fragment of SP, SP-(7-11), increased PGE2 and collagenase production at concentrations greater than 1 mM.
-
产品描述Substance P (7-11) is a C-terminal fragment of Substance P, which can cause an increase in the intracellular calcium concentration as measured by the fluorescent dye Fura-2. In addition, the C-terminal fragment of SP, SP-(7-11), increased PGE2 and collagenase production at concentrations greater than 1 mM.(In Vitro):Substance P (7-11) increases PGE2 and collagenase production at concentrations greater than 1 μM. Substance P (7-11), but not intact SP, SP-(1-4), SP-(1-6), SP- (8-11) or SP-(9-1 1), nor the tachykinins NKA and NKB, causes an increase in the intracellular calcium concentration as measured by the fluorescent dye Fura-2. The maximal change in intracellular calcium induced by 10 μM Substance P (7-11) was 140±30 nM.
-
同义词——
-
通路Others
-
靶点Other Targets
-
受体——
-
研究领域——
-
适应症——
化学信息
-
CAS Number51165-05-0
-
分子量612.8
-
分子式C31H44N6O5S
-
纯度>98% (HPLC)
-
溶解度——
-
SMILES——
-
化学全称Sequence:Phe-Phe-Gly-Leu-Met-NH2
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
Halliday DA, et al. The substance P fragment SP-(7-11) increases prostaglandin E2, intracellular Ca2+ and collagenase production in bovine articular chondrocytes. Biochem J. 1993 May 15;292 ( Pt 1):57-62.
产品手册
关联产品
-
Homoveratrumic acid
Papaverine intermediate, used to synthesis cardiovascular drugs, such as verapamil, bevantolol, etc.
-
Cimifugin 4-O-beta-D...
Cimifugin 4'-O-beta-D-glucopyranoside is a natural product.
-
6'-Hydroxy-3,4,2',3'...
6'-Hydroxy-3,4,2',3',4'-pentamethoxychalcone is an alkenylphenol from Piper obliquum with antiinflammatory and antibacterial activities.